Pharmaceutical Analysis by Polarography. VIII

Electrochemical Analysis of Antichemotherapeutic Drug Zanosar in Pharmaceutical and Biological Samples by Differential Pulse Polarography

The electrochemical reduction of zanosar was investigated systematically by direct current polarography, cyclic voltammetry, and differential pulse polarography (DPP). A simple DPP technique was proposed for the direct quantitative determination of anticancer drug zanosar in pharmaceutical formulation and spiked human urine samples for the first time. The reduction potential was -0.28 V versus ...

Analysis of Pesticide Residues by Polarography

Polarography in Molten Salts

TYPES OF MELTS From the practical viewpoint, melts may be classified according to melting points which may limit the available techniques. The lowest melting, with working temperatures up to 250°, are typified by the LiNO3—NaNO3— KNO3 eutectic, NaNO3—KNO3 eutectic, LiClO4, and ammonium formate. With these solvents it is possible to use the dropping mercury electrode, or hanging mercury drop ele...

Pharmaceutical target identification by gene expression analysis.

The majority of newly-identified genes in the human genome show no significant sequence similarity to genes whose function is known, so they are not easily recognized as potential drug targets. Expression analysis is an alternative method to suggest possible functions of genes. We review statistical methods for gene expression analysis to identify potential pharmaceutical targets. Specifically,...

Characterization of Pharmaceutical Materials by Thermal Analysis

Thermal analysis has been an extremely important analytical tool within the pharmaceutical industry for more than forty (40) years. Although the technique could easily be classified as mature, recent advances in Differential Scanning Calorimetry (DSC) have generated renewed enthusiasm in thermal analysis from pharmaceutical scientists. These new developments include TzeroTM DSC and Modulated DS...